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"Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq" Replogle et al. 2022 - commonly requested supplemental files

dataset
posted on 2022-11-29, 01:57 authored by Joseph ReplogleJoseph Replogle, Jonathan Weissman

Commonly requested supplemental files supporting the publication:  

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq, Replogle, Joseph M. et al. Cell, Volume 185, Issue 14, 2559 - 2575.e28 https://doi.org/10.1016/j.cell.2022.05.013:


1) All Anderson-Darling p-values for differential expression analysis


2) Embedding coordinates for Figure 2D


3) Downloadable interactive scatter plot of Fig. 2D


4) Z-normalized expression data used to make Figs. 2 and 4, annotated with the cluster identities from Supplementary Table 3


See related datasets at: 

https://doi.org/10.25452/figshare.plus.20029387

https://doi.org/10.25452/figshare.plus.20127869

https://doi.org/10.25452/figshare.plus.20022944

Funding

DARPA HR0011-19-2-0007

Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease

National Human Genome Research Institute

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The role of TMA7 in mitochondrial dysfunction

National Institute of Neurological Disorders and Stroke

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Predictive engineering of cellular transcriptional state

National Institute of General Medical Sciences

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Cancer Center Support Grant

National Cancer Institute

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History

Research Institution(s)

University of California, San Francisco; Whitehead Institute

Contact email

joseph@wi.mit.edu

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