iPSCORE Multiomic QTLs: Phenotype Count Matrices
This directory contains one sample metadata file and eight count files corresponding to the gene, ATAC-seq peak, and H3K27ac ChIP-seq peak counts from three tissues from the iPSCORE Collection; induced pluripotent stem cells (iPSCs), iPSC-derived cardiovascular progenitor cells (CVPCs), and iPSC-derived pancreatic progenitor cells (PPCs).
Each file has the same format. The first column contains the identifier for the molecular element (gene or peak) and the remaining column corresponds to the phenotype (sample) identifier found in the SampleMetadata file. The SampleMetadata is identical to Supplemental Table 2 in the publication. Please see the Table legends in the linked publication for more details.
The labeling convention is [tissue_phenotype_counts.txt].
Funding
San Diego Biomedical Informatics Education & Research (SABER)
United States National Library of Medicine
Find out more...Pancreas cell type-specific regulatory variants and T2D disease risk association
National Institute of Diabetes and Digestive and Kidney Diseases
Find out more...Functional Analysis of T2D Associated Non-coding SNPs
National Institute of Diabetes and Digestive and Kidney Diseases
Find out more...Fine-mapping and functional analysis of T1D-associated variants
National Institute of Diabetes and Digestive and Kidney Diseases
Find out more...Diabetes Research Center (DRC)
National Institute of Diabetes and Digestive and Kidney Diseases
Find out more...Cardiac stage-specific regulatory variants and their disease risk association
National Heart Lung and Blood Institute
Find out more...REGULATORY GENOMIC STUDIES IN A COHORT OF IPS CELL DERIVED CARDIOMYOCYTES
National Heart Lung and Blood Institute
Find out more...Genetic & Social Determinants of Health: Center for Admixture Science and Technology
National Human Genome Research Institute
Find out more...Optimizing HaploSeq for whole-genome phased haplotypes in biomedical applications
National Human Genome Research Institute
Find out more...Center of Excellence for Stem Cell Genomics – Salk
California Institute for Regenerative Medicine
Find out more...History
Research Institution(s)
University of California, San DiegoContact email
tdarthur40@gmail.comAssociated Preprint DOI
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