Dataset supporting the study "Neuromodulatory effects of theta-burst stimulation of the prefrontal cortex using TMS-EEG"
Theta burst stimulation (TBS) is a new form of repetitive transcranial magnetic stimulation (TMS) capable of non-invasively modulating cortical excitability. In recent years TBS has been increasingly used as a neuroscientific investigative tool and therapeutic intervention for psychiatric disorders, in which the dorsolateral prefrontal cortex (DLPFC) is often the primary target. However, the neuromodulatory effects of TBS on prefrontal regions remain unclear. Here we share EEG recordings and structural MRI scans from twenty-four healthy participants who received intermittent TBS (two sessions), continuous TBS (two sessions), and sham stimulation (one session) applied to the left DLPFC using a double-blinded crossover design. Each session includes eyes-open resting-state EEG and single-pulse TMS-EEG obtained before TBS and 2-, 15-, and 30-min post-stimulation. This dataset together with the Matlab codes used for its analysis enables foundational basic science investigations into the neuromodulatory effects of TBS on the DLPFC.